Any feedback?
Please rate this page
(literature.php)
(0/150)

BRENDA support

Literature summary for 3.1.6.12 extracted from

  • Auclair, D.; Finnie, J.; White, J.; Nielsen, T.; Fuller, M.; Kakkis, E.; Cheng, A.; ONeill, C.; Hopwood, J.
    Repeated intrathecal injections of recombinant human 4-sulphatase remove dural storage in mature mucopolysaccharidosis VI cats primed with a short-course tolerisation regimen (2010), Mol. Genet. Metab., 99, 132-141.
    View publication on PubMed

Application

Application Comment Organism
additional information a relatively high rate of immunotolerance towards recombinant human N-acetylgalactosamine-4-sulfatase can be achieved in MPS-VI cats with a shortcourse tolerisation regimen ultimately permitting removal of lysosomal storage within the dura mater with the use of intrathecal therapy Homo sapiens

Organism

Organism UniProt Comment Textmining
Homo sapiens
-
-
-

Source Tissue

Source Tissue Comment Organism Textmining
commercial preparation recombinant enzyme Homo sapiens
-

Synonyms

Synonyms Comment Organism
4-sulphatase
-
Homo sapiens
ASB
-
Homo sapiens
N-acetylgalactosamine-4-sulphatase
-
Homo sapiens

General Information

General Information Comment Organism
additional information a relatively high rate of immunotolerance towards recombinant human N-acetylgalactosamine-4-sulfatase can be achieved in MPS-VI cats with a shortcourse tolerisation regimen ultimately permitting removal of lysosomal storage within the dura mater with the use of intrathecal therapy Homo sapiens