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Literature summary for 3.1.6.12 extracted from

  • Nicholls, R.G.; Roy, A.B.
    Arylsulfatases (1971), The Enzymes, 3rd Ed. (Boyer, P. D. , ed. ), 5, 21-41.
No PubMed abstract available
Search for more literature for 3.1.6.12

Activating Compound

Activating Compound Comment Organism Structure
acetate
-
 Bos taurus

Inhibitors

Inhibitors Comment Organism Structure
SO42-
-
 Bos taurus
SO42-
-
 Macropus sp.

KM Value [mM]

KM Value [mM] KM Value Maximum [mM] Substrate Comment Organism Structure
1.86
-
 nitrocatechol 4-sulfate
-
 Bos taurus
10.8
-
 p-Nitrophenyl sulfate
-
 Bos taurus

Metals/Ions

Metals/Ions Comment Organism Structure
Cl- activation Bos taurus

Molecular Weight [Da]

Molecular Weight [Da] Molecular Weight Maximum [Da] Comment Organism
45000
-
 gel filtration Bos taurus

Natural Substrates/ Products (Substrates)

Natural Substrates Organism Comment (Nat. Sub.) Natural Products Comment (Nat. Pro.) Rev. Reac.
N-acetyl-D-galactosamine 4-sulfate units + H2O Homo sapiens acts also on N-acetylglucosamine 4-sulfate N-acetyl-D-galactosamine units + sulfate
-
 ?
N-acetyl-D-galactosamine 4-sulfate units + H2O Bos taurus acts also on N-acetylglucosamine 4-sulfate N-acetyl-D-galactosamine units + sulfate
-
 ?
N-acetyl-D-galactosamine 4-sulfate units + H2O Macropus sp. acts also on N-acetylglucosamine 4-sulfate N-acetyl-D-galactosamine units + sulfate
-
 ?

Organism

Organism UniProt Comment Textmining
Bos taurus
-
-
-
Homo sapiens
-
-
-
Macropus sp.
-
-
-

Source Tissue

Source Tissue Comment Organism Textmining
brain
-
 Homo sapiens
-
liver
-
 Homo sapiens
-
liver
-
 Bos taurus
-

Substrates and Products (Substrate)

Substrates Comment Substrates Organism Products Comment (Products) Rev. Reac.
N-acetyl-D-galactosamine 4-sulfate units + H2O acts also on N-acetylglucosamine 4-sulfate Homo sapiens N-acetyl-D-galactosamine units + sulfate
-
 ?
N-acetyl-D-galactosamine 4-sulfate units + H2O acts also on N-acetylglucosamine 4-sulfate Bos taurus N-acetyl-D-galactosamine units + sulfate
-
 ?
N-acetyl-D-galactosamine 4-sulfate units + H2O acts also on N-acetylglucosamine 4-sulfate Macropus sp. N-acetyl-D-galactosamine units + sulfate
-
 ?
p-nitrocatechol sulfate + H2O
-
 Bos taurus p-nitrocatechol + sulfate
-
 ?
p-nitrocatechol sulfate + H2O enzymes catalyze in addition to reaction of EC 3.1.6.12 also arylsulfatase reaction , see also EC 3.1.6.1 Homo sapiens p-nitrocatechol + sulfate
-
 ?
p-nitrophenyl sulfate + H2O
-
 Bos taurus p-nitrophenol + sulfate
-
 ?