Literature summary for 3.1.6.1 extracted from

Morena, F.; di Girolamo, I.; Emiliani, C.; Gritti, A.; Biffi, A.; Martino, S.
A new analytical bench assay for the determination of arylsulfatase A activity toward galactosyl-3-sulfate ceramide: implication for metachromatic leukodystrophy diagnosis (2014), Anal. Chem., 86, 473-481.

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Application

Application	Comment	Organism
medicine	assay for the diagnosis of metachromatic leukodystrophy. Determination of arylsulfatase A activity toward the natural substrate, galactosyl-3-sulfate ceramide or sulfatide, is performed using neat sulfatide without chemical modification. The hydrolyzed sulfatide is monitored upon inclusion of the colorimetric reagent Azure A. Within a clinical context, the method definitely discriminates between healthy subject samples and metachromatic leukodystrophy patient samples	Homo sapiens

Organism

Organism	UniProt	Comment	Textmining
Homo sapiens	P15289	-	-

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Release 2023.1 (January 2023)