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Literature summary for 3.1.6.1 extracted from
- Isomer specifici kinetics of dopamine beta-hydroxylase and arylsulfatase towards catecholamine sulfates (1990), Biochem. Int., 20, 343-351.
KM Value [mM]
| KM Value [mM] | KM Value Maximum [mM] | Substrate | Comment | Organism | Structure |
|---|---|---|---|---|---|
| 0.68 | - |
4-nitrocatechol sulfate | arylsulfatase B | Sus scrofa |  |
| 1.9 | - |
epinephrine 4-sulfate | pH 6.9 | Sus scrofa | |
| 2.1 | - |
dopamine 4-sulfate | pH 6.9 | Sus scrofa | |
| 2.5 | - |
epinephrine 4-sulfate | pH 7.4 | Sus scrofa | |
| 2.7 | - |
norepinephrine 4-sulfate | pH 6.9 | Sus scrofa | |
| 2.8 | - |
dopamine 4-sulfate | pH 7.4 | Sus scrofa | |
| 3.2 | - |
4-nitrocatechol sulfate | arylsulfatase A | Sus scrofa | |
| 3.3 | - |
norepinephrine 4-sulfate | pH 7.4 | Sus scrofa | |
| 7.2 | - |
dopamine 3-sulfate | pH 6.9 | Sus scrofa | |
| 9.8 | - |
dopamine 3-sulfate | pH 7.4 | Sus scrofa | |
| 10.5 | - |
norepinephrine 3-sulfate | pH 6.9 | Sus scrofa | |
| 12.8 | - |
norepinephrine 3-sulfate | pH 7.4 | Sus scrofa | |
| 14.1 | - |
epinephrine 3-sulfate | pH 6.9 | Sus scrofa | |
| 18 | - |
epinephrine 3-sulfate | pH 7.4 | Sus scrofa | |
Natural Substrates/ Products (Substrates)
| Natural Substrates | Organism | Comment (Nat. Sub.) | Natural Products | Comment (Nat. Pro.) | Rev. | Reac. |
|---|---|---|---|---|---|---|
| additional information | Homo sapiens | enzyme might be of physiological significance in the deconjugation of the catecholamine sulfate isomers | ? | - |
? | |
Organism
| Organism | UniProt | Comment | Textmining |
|---|---|---|---|
| Homo sapiens | - |
- |
- |
| Sus scrofa | - |
- |
- |
Purification (Commentary)
| Purification (Comment) | Organism |
|---|---|
| partial, arylsulfatase A and B | Sus scrofa |
Source Tissue
| Source Tissue | Comment | Organism | Textmining |
|---|---|---|---|
| liver | - |
Homo sapiens | - |
| liver | - |
Sus scrofa | - |
Substrates and Products (Substrate)
| Substrates | Comment Substrates | Organism | Products | Comment (Products) | Rev. | Reac. |
|---|---|---|---|---|---|---|
| 4-nitrocatechol sulfate + H2O | - |
Homo sapiens | 4-nitrocatechol + sulfate | - |
? | |
| 4-nitrocatechol sulfate + H2O | - |
Sus scrofa | 4-nitrocatechol + sulfate | - |
? | |
| dopamine 3-sulfate + H2O | - |
Sus scrofa | dopamine + sulfate | - |
? | |
| dopamine 4-sulfate + H2O | - |
Sus scrofa | dopamine + sulfate | - |
? | |
| epinephrine 3-sulfate + H2O | - |
Sus scrofa | epinephrine + sulfate | - |
? | |
| epinephrine 4-sulfate + H2O | - |
Sus scrofa | epinephrine + sulfate | - |
? | |
| additional information | enzyme might be of physiological significance in the deconjugation of the catecholamine sulfate isomers | Homo sapiens | ? | - |
? | |
| nordopamine 3-sulfate + H2O | - |
Sus scrofa | nordopamine + sulfate | - |
? | |
| norepinephrine 3-sulfate + H2O | - |
Sus scrofa | norepinephrine + sulfate | - |
? | |
| norepinephrine 4-sulfate + H2O | - |
Sus scrofa | norepinephrine + sulfate | - |
? | |
Synonyms
| Synonyms | Comment | Organism |
|---|---|---|
| arylsulfatase type VI | - |
Sus scrofa |
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