Data extracted from this reference:
Organism
Borreliella burgdorferi
O51564
enzyme is a DHH-DHHA1 domain protein
Borreliella burgdorferi DSM 4680
O51564
enzyme is a DHH-DHHA1 domain protein
Subunits
More
PdeA is a DHH-DHHA1 domain protein
Borreliella burgdorferi
Synonyms
BB0619
Borreliella burgdorferi
Dhhp
Borreliella burgdorferi
Subunits (protein specific)
More
PdeA is a DHH-DHHA1 domain protein
Borreliella burgdorferi
General Information
physiological function
DhhP is essential for Borrelia burgdorferi growth both in vitro and in the mammalian host. The conditional DhhP mutant has a dramatic increase in intracellular c-di-AMP level in comparison to the isogenic wild-type strain. Elevated cellular c-di-AMP in Borrelia burgdorferi does not result in an increased resistance to beta-lactamase antibiotics. The DhhP mutant is defective in induction of the sigmaS factor, RpoS, and the RpoS-dependent outer membrane virulence factor OspC
Borreliella burgdorferi
General Information (protein specific)
physiological function
DhhP is essential for Borrelia burgdorferi growth both in vitro and in the mammalian host. The conditional DhhP mutant has a dramatic increase in intracellular c-di-AMP level in comparison to the isogenic wild-type strain. Elevated cellular c-di-AMP in Borrelia burgdorferi does not result in an increased resistance to beta-lactamase antibiotics. The DhhP mutant is defective in induction of the sigmaS factor, RpoS, and the RpoS-dependent outer membrane virulence factor OspC
Borreliella burgdorferi
Other publictions for EC 3.1.4.60
751077
Bowman
New insights into the cyclic ...
Staphylococcus aureus
J. Biol. Chem.
291
26970-26986
2016
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750844
Tang
Functional analysis of a c-di ...
Mycolicibacterium smegmatis, Mycolicibacterium smegmatis ATCC 700084
Int. J. Biol. Sci.
11
813-824
2015
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750731
Ye
DhhP, a cyclic di-AMP phospho ...
Borreliella burgdorferi, Borreliella burgdorferi DSM 4680
Infect. Immun.
82
1840-1849
2014
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750954
Bai
Two DHH subfamily 1 proteins ...
Streptococcus pneumoniae serotype 2, Streptococcus pneumoniae serotype 2 D39
J. Bacteriol.
195
5123-5132
2013
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