Organism | UniProt | Comment | Textmining |
---|---|---|---|
Borreliella burgdorferi | O51564 | enzyme is a DHH-DHHA1 domain protein | - |
Borreliella burgdorferi DSM 4680 | O51564 | enzyme is a DHH-DHHA1 domain protein | - |
Subunits | Comment | Organism |
---|---|---|
More | PdeA is a DHH-DHHA1 domain protein | Borreliella burgdorferi |
Synonyms | Comment | Organism |
---|---|---|
BB0619 | - |
Borreliella burgdorferi |
Dhhp | - |
Borreliella burgdorferi |
General Information | Comment | Organism |
---|---|---|
physiological function | DhhP is essential for Borrelia burgdorferi growth both in vitro and in the mammalian host. The conditional DhhP mutant has a dramatic increase in intracellular c-di-AMP level in comparison to the isogenic wild-type strain. Elevated cellular c-di-AMP in Borrelia burgdorferi does not result in an increased resistance to beta-lactamase antibiotics. The DhhP mutant is defective in induction of the sigmaS factor, RpoS, and the RpoS-dependent outer membrane virulence factor OspC | Borreliella burgdorferi |