Cloned (Comment) | Organism |
---|---|
transient expression of the engineered human PDE4A10 open reading frame in COS7 cells allows detection of a 121000 Da protein in both soluble and particulate fractions. PDE4A10 is localized primarily to the perinuclear region of COS7 cells | Homo sapiens |
Inhibitors | Comment | Organism | Structure |
---|---|---|---|
rolipram | - |
Homo sapiens |
Organism | UniProt | Comment | Textmining |
---|---|---|---|
Homo sapiens | - |
- |
- |
Substrates | Comment Substrates | Organism | Products | Comment (Products) | Rev. | Reac. |
---|---|---|---|---|---|---|
adenosine 3',5'-cyclic phosphate + H2O | - |
Homo sapiens | adenosine 5'-phosphate | - |
? |
Synonyms | Comment | Organism |
---|---|---|
cyclic AMP-specific phosphodiesterase | - |
Homo sapiens |
PDE4A10 | - |
Homo sapiens |
Temperature Stability Minimum [°C] | Temperature Stability Maximum [°C] | Comment | Organism |
---|---|---|---|
55 | - |
soluble HSPDE4A10 is more thermostable (T0.5: 11 min) than the particulate enzyme (T0.5: 5 min) | Homo sapiens |
IC50 Value | IC50 Value Maximum | Comment | Organism | Inhibitor | Structure |
---|---|---|---|---|---|
0.00005 | - |
- |
Homo sapiens | rolipram |