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Literature summary for 3.1.4.53 extracted from

  • Huston, E.; Gall, I.; Houslay, T.M.; Houslay, M.D.
    Helix-1 of the cAMP-specific phosphodiesterase PDE4A1 regulates its phospholipase-D-dependent redistribution in response to release of Ca2+ (2006), J. Cell Sci., 119, 3799-3810.
    View publication on PubMed

Cloned(Commentary)

Cloned (Comment) Organism
expression in COS1 cells Rattus norvegicus

Localization

Localization Comment Organism GeneOntology No. Textmining
membrane helix-1 is important for intracellular targeting of PDE4A1 in living cells, facilitating membrane association, targeting to the trans-Golgi stack and conferring Ca2+-stimulated intracellular redistribution in a manner that is dependent on the phospholipase-D-mediated generation of phosphatidic acid Rattus norvegicus 16020
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Organism

Organism UniProt Comment Textmining
Rattus norvegicus P54748
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Synonyms

Synonyms Comment Organism
PDE4A1
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Rattus norvegicus