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Literature summary for 3.1.4.53 extracted from

  • Amegadzie, B.Y.; Hanning, C.R.; McLaughlin, M.M.; Burman, M.; Cieslinski, L.B.; Livi, G.P.; Torphy, T.J.
    Characterization of two human cAMP-specific phosphodiesterase subtypes expressed in baculovirus-infected insect cells (1995), Cell Biol. Int., 19, 477-484.
    View publication on PubMed
Search for more literature for 3.1.4.53

Cloned(Commentary)

Cloned (Comment) Organism
expression in Spodoptera frugiperda Homo sapiens

Inhibitors

Inhibitors Comment Organism Structure
R-rolipram
-
 Homo sapiens

KM Value [mM]

KM Value [mM] KM Value Maximum [mM] Substrate Comment Organism Structure
0.003
-
 adenosine 3',5'-cyclic phosphate
-
 Homo sapiens
0.0038
-
 adenosine 3',5'-cyclic phosphate
-
 Homo sapiens

Organism

Organism UniProt Comment Textmining
Homo sapiens
-
-
-

Substrates and Products (Substrate)

Substrates Comment Substrates Organism Products Comment (Products) Rev. Reac.
adenosine 3',5'-cyclic phosphate + H2O
-
 Homo sapiens adenosine 5'-phosphate
-
 ?
additional information no activity with cGMP Homo sapiens ?
-
 ?

Synonyms

Synonyms Comment Organism
hPDE4A
-
 Homo sapiens
hPDE4B
-
 Homo sapiens

Ki Value [mM]

Ki Value [mM] Ki Value maximum [mM] Inhibitor Comment Organism Structure
0.00025
-
 R-rolipram
-
 Homo sapiens
0.00038
-
 R-rolipram
-
 Homo sapiens