Protein Variants | Comment | Organism |
---|---|---|
D448N | mutation in conserved active site residue, loss of enzyme function does not affect steady-state acetylcholine release or reception | Caenorhabditis elegans |
Natural Substrates | Organism | Comment (Nat. Sub.) | Natural Products | Comment (Nat. Pro.) | Rev. | Reac. |
---|---|---|---|---|---|---|
additional information | Caenorhabditis elegans | isoform PDE4 regulates both GalphaS-dependent and GalphaS-indeoendent cAMP pools in the neurons controling locomotion rate | ? | - |
? |
Organism | UniProt | Comment | Textmining |
---|---|---|---|
Caenorhabditis elegans | - |
- |
- |
Source Tissue | Comment | Organism | Textmining |
---|---|---|---|
nervous system | strong expression of isoform PDE4 throughout the nervous system | Caenorhabditis elegans | - |
Substrates | Comment Substrates | Organism | Products | Comment (Products) | Rev. | Reac. |
---|---|---|---|---|---|---|
additional information | isoform PDE4 regulates both GalphaS-dependent and GalphaS-indeoendent cAMP pools in the neurons controling locomotion rate | Caenorhabditis elegans | ? | - |
? |