Literature summary for 3.1.4.50 extracted from

Jin, J.K.; Jang, B.; Jin, H.T.; Choi, E.K.; Jung, C.G.; Akatsu, H.; Kim, J.I.; Carp, R.I.; Kim, Y.S.
Phosphatidylinositol-glycan-phospholipase D is involved in neurodegeneration in prion disease (2015), PLoS ONE, 10, e0122120 .

Search for more literature for 3.1.4.50

Application

Application	Comment	Organism
medicine	the expression of GPI-PLD is dramatically down-regulated in both the brain and cerebrospinal fluids of Creutzfeldt-Jakob disease patients, while no differences in expression are observed in either the brains or cerebrospinal fluids specimens from Alzheimer's disease patients	Homo sapiens
medicine	the expression of GPI-PLD is dramatically down-regulated in the brains of scrapie-infected mice, especially in the caveolin-enriched membrane fractions. The decrease in GPI-PLD expression levels begins at the same time that prion proteins begin to accumulate in the infected brains	Mus musculus

Organism

Organism	UniProt	Comment	Textmining
Homo sapiens	P80108	-	-
Mus musculus	O70362	-	-

Source Tissue

Source Tissue	Comment	Organism	Textmining
brain	-	Mus musculus	-
brain	-	Homo sapiens	-

Use of this online version of BRENDA is free under the CC BY 4.0 license. See terms of use for full details.

Release 2023.1 (January 2023)