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Literature summary for 3.1.4.44 extracted from

  • Yanaka, N.; Nogusa, Y.; Fujioka, Y.; Yamashita, Y.; Kato, N.
    Involvement of membrane protein GDE2 in retinoic acid-induced neurite formation in Neuro2A cells (2007), FEBS Lett., 581, 712-718.
    View publication on PubMed

Cloned(Commentary)

Cloned (Comment) Organism
expressed as GST-tag fusion protein in Escherichia coli BL21(DE3) Gold Homo sapiens

Localization

Localization Comment Organism GeneOntology No. Textmining
endoplasmic reticulum
-
Homo sapiens 5783
-
Golgi apparatus
-
Homo sapiens 5794
-
membrane
-
Homo sapiens 16020
-
membrane integral membrane protein Mus musculus 16020
-
mitochondrion
-
Homo sapiens 5739
-
plasma membrane
-
Homo sapiens 5886
-
vacuole
-
Homo sapiens 5773
-

Molecular Weight [Da]

Molecular Weight [Da] Molecular Weight Maximum [Da] Comment Organism
37700
-
x * 37700, calculated from the deduced amino acid sequence Homo sapiens

Natural Substrates/ Products (Substrates)

Natural Substrates Organism Comment (Nat. Sub.) Natural Products Comment (Nat. Pro.) Rev. Reac.
glycerophosphoinositol + H2O Homo sapiens
-
glycerol 3-phosphate + inositol
-
?
glycerophosphoinositol + H2O Mus musculus enzyme selectively hydrolyzes glycerophosphoinositol glycerol 3-phosphate + inositol
-
?

Organism

Organism UniProt Comment Textmining
Homo sapiens Q9NZC3
-
-
Mus musculus
-
-
-

Posttranslational Modification

Posttranslational Modification Comment Organism
additional information several potential phosphorylation sites detected, possible regulation by kinase phosphorylation Homo sapiens

Source Tissue

Source Tissue Comment Organism Textmining
brain DNA-template obtained from a brain cDNA library Homo sapiens
-

Substrates and Products (Substrate)

Substrates Comment Substrates Organism Products Comment (Products) Rev. Reac.
glycerophosphoinositol + H2O
-
Homo sapiens glycerol 3-phosphate + inositol
-
?
glycerophosphoinositol + H2O enzyme selectively hydrolyzes glycerophosphoinositol Mus musculus glycerol 3-phosphate + inositol
-
?

Subunits

Subunits Comment Organism
? x * 37700, calculated from the deduced amino acid sequence Homo sapiens

Synonyms

Synonyms Comment Organism
GDE1
-
Mus musculus
GDE1
-
Homo sapiens
GDE1/MIR16
-
Homo sapiens
glycerophosphoinositol phosphodiesterase
-
Homo sapiens
membrane interacting protein of regulator of G protein signaling 16
-
Homo sapiens
membrane interacting protein of RGS16
-
Homo sapiens
MIR16
-
Homo sapiens

pI Value

Organism Comment pI Value Maximum pI Value
Homo sapiens calculated from the deduced amino acid sequence
-
6.51