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Literature summary for 3.1.4.41 extracted from

  • Gellings, P.S.; McGee, D.J.
    Arcanobacterium haemolyticum utilizes both phospholipase D and arcanolysin to mediate its uptake into non-phagocytic cells (2019), Infect. Immun., 87, e00832-18 .
    View publication on PubMedView publication on EuropePMC
Search for more literature for 3.1.4.41

Cloned(Commentary)

Cloned (Comment) Organism
expressed in Escherichia coli DH5alpha cells Arcanobacterium haemolyticum

Natural Substrates/ Products (Substrates)

Natural Substrates Organism Comment (Nat. Sub.) Natural Products Comment (Nat. Pro.) Rev. Reac.
sphingomyelin + H2O Arcanobacterium haemolyticum
-
 ceramide phosphate + choline
-
 ?

Organism

Organism UniProt Comment Textmining
Arcanobacterium haemolyticum
-
-
-

Purification (Commentary)

Purification (Comment) Organism
Ni-NTA resin column chromatography Arcanobacterium haemolyticum

Substrates and Products (Substrate)

Substrates Comment Substrates Organism Products Comment (Products) Rev. Reac.
sphingomyelin + H2O
-
 Arcanobacterium haemolyticum ceramide phosphate + choline
-
 ?

Synonyms

Synonyms Comment Organism
phospholipase D
-
 Arcanobacterium haemolyticum
PLD
-
 Arcanobacterium haemolyticum
sphingomyelin-specific phospholipase D
-
 Arcanobacterium haemolyticum

General Information

General Information Comment Organism
physiological function Arcanobacterium haemolyticum utilizes phospholipase D to mediate its uptake into non-phagocytic cell. The sphingomyelinase activity of phospholipase D is necessary to increase bacterial adherence to Detroit 562 cells Arcanobacterium haemolyticum