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Literature summary for 3.1.4.41 extracted from
- Red blood cell lysis induced by the venom of brown recluse spider (1978), Arch. Biochem. Biophys., 187, 355-365.
Natural Substrates/ Products (Substrates)
| Natural Substrates | Organism | Comment (Nat. Sub.) | Natural Products | Comment (Nat. Pro.) | Rev. | Reac. |
|---|---|---|---|---|---|---|
| additional information | Loxosceles reclusa | sphingomyelin of the red cell membrane is hydrolyzed by a sphingomyelinase D-type activity expressed by venom hemolysin | ? | - |
? |  |
Organism
| Organism | UniProt | Comment | Textmining |
|---|---|---|---|
| Loxosceles reclusa | - |
brown recluse spider | - |
Source Tissue
| Source Tissue | Comment | Organism | Textmining |
|---|---|---|---|
| venom gland | - |
Loxosceles reclusa | - |
Substrates and Products (Substrate)
| Substrates | Comment Substrates | Organism | Products | Comment (Products) | Rev. | Reac. |
|---|---|---|---|---|---|---|
| additional information | sphingomyelin of the red cell membrane is hydrolyzed by a sphingomyelinase D-type activity expressed by venom hemolysin | Loxosceles reclusa | ? | - |
? | |
| sphingomyelin + H2O | - |
Loxosceles reclusa | N-acylsphingosylphosphate + choline | - |
? | |
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Release 2023.1 (January 2023)
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