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Literature summary for 3.1.4.40 extracted from

  • Masson, L.; Holbein, B.E.
    Physiology of sialic acid capsular polysaccharide synthesis in serogroup B Neisseria meningitidis (1983), J. Bacteriol., 154, 728-736.
    View publication on PubMedView publication on EuropePMC
Search for more literature for 3.1.4.40

Inhibitors

Inhibitors Comment Organism Structure
CMP complete inhibition at 0.0453 mM Neisseria meningitidis

KM Value [mM]

KM Value [mM] KM Value Maximum [mM] Substrate Comment Organism Structure
0.00088
-
 CMP-N-acylneuraminate
-
 Neisseria meningitidis

Localization

Localization Comment Organism GeneOntology No. Textmining
plasma membrane cytoplasmic Neisseria meningitidis 5886
-

Metals/Ions

Metals/Ions Comment Organism Structure
Mg2+ 20 mM MgCl2 is optimal for stimulation Neisseria meningitidis

Natural Substrates/ Products (Substrates)

Natural Substrates Organism Comment (Nat. Sub.) Natural Products Comment (Nat. Pro.) Rev. Reac.
CMP-N-acylneuraminate + H2O Neisseria meningitidis
-
 ?
-
 ir
CMP-N-acylneuraminate + H2O Neisseria meningitidis PRM102
-
 ?
-
 ir

Organism

Organism UniProt Comment Textmining
Neisseria meningitidis
-
-
-

Purification (Commentary)

Purification (Comment) Organism
-
 Neisseria meningitidis

Specific Activity [micromol/min/mg]

Specific Activity Minimum [µmol/min/mg] Specific Activity Maximum [µmol/min/mg] Comment Organism
additional information
-
-
 Neisseria meningitidis

Substrates and Products (Substrate)

Substrates Comment Substrates Organism Products Comment (Products) Rev. Reac.
CMP-N-acylneuraminate + H2O
-
 Neisseria meningitidis CMP + N-acylneuraminate
-
 ir
CMP-N-acylneuraminate + H2O
-
 Neisseria meningitidis PRM102 CMP + N-acylneuraminate
-
 ir
CMP-N-acylneuraminate + H2O
-
 Neisseria meningitidis ?
-
 ir
CMP-N-acylneuraminate + H2O
-
 Neisseria meningitidis PRM102 ?
-
 ir

pH Optimum

pH Optimum Minimum pH Optimum Maximum Comment Organism
7.7
-
-
 Neisseria meningitidis