Any feedback?
Please rate this page
(literature.php)
(0/150)

BRENDA support

Literature summary for 3.1.4.4 extracted from

  • Ray, S.; Chen, Y.; Ayoung, J.; Hanna, R.; Brazill, D.
    Phospholipase D controls Dictyostelium development by regulating G protein signaling (2011), Cell. Signal., 23, 335-343.
    View publication on PubMedView publication on EuropePMC
Search for more literature for 3.1.4.4

Protein Variants

Protein Variants Comment Organism
additional information construction of a pldB disruption mutant by nucleotide replacement Dictyostelium discoideum

Organism

Organism UniProt Comment Textmining
Dictyostelium discoideum
-
 gene pldB
-
Dictyostelium discoideum AX3
-
 gene pldB
-

Substrates and Products (Substrate)

Substrates Comment Substrates Organism Products Comment (Products) Rev. Reac.
phosphatidylcholine + H2O a phospholipid transphosphatidylation reaction Dictyostelium discoideum phosphatidic acid + choline
-
 ?
phosphatidylcholine + H2O a phospholipid transphosphatidylation reaction Dictyostelium discoideum AX3 phosphatidic acid + choline
-
 ?

Synonyms

Synonyms Comment Organism
PldB
-
 Dictyostelium discoideum

General Information

General Information Comment Organism
malfunction cells lacking PldB preferentially sort to the stalk in chimeric fruiting bodies with wild-type cells Dictyostelium discoideum
metabolism PldB mediates quorum sensing in the CMF pathway and regulates the dissociation of G protein Galpha2betagamma Dictyostelium discoideum
physiological function PldB regulates cAMP chemotaxis, overview. Phospholipase D controls Dictyostelium development by regulating G protein signaling, its activity is required for CMF to alter the kinetics of cAMP-induced G protein signaling, overview Dictyostelium discoideum