Cloned (Comment) | Organism |
---|---|
gene pld, DNA and amino acid sequence determination and analysis, A1S_2989 locus is predicted to encode a 368-amino-acid protein that contains two putative PLD active-site motifs, a perfect consensus motif spanning amino acid residues 15 to 30 and a nearly perfect match missing a single amino acid within the X6 region of the active-site motif spanning amino acid residues 265 to 279, gene locus A1S_2989 modulates phospholipase D activity | Acinetobacter baumannii |
Protein Variants | Comment | Organism |
---|---|---|
additional information | generation of an Acinetobacter baumannii strain 98-37-09 transposon mutant library using the EZ-Tn5 R6Kori/KAN-2 Tnp transposome system, construction of the ACJ2, A1S_2989 mutant. Disruption of phospholipase D causes a reduction in the organism's ability to thrive in serum, a deficiency in epithelial cell invasion, and diminished pathogenesis in a murine model of pneumonia | Acinetobacter baumannii |
Organism | UniProt | Comment | Textmining |
---|---|---|---|
Acinetobacter baumannii | - |
strain ATCC 19606 | - |
Synonyms | Comment | Organism |
---|---|---|
PLD | - |
Acinetobacter baumannii |
General Information | Comment | Organism |
---|---|---|
malfunction | disruption of phospholipase D causes a reduction in the organism's ability to thrive in serum, a deficiency in epithelial cell invasion, and diminished pathogenesis in a murine model of pneumonia | Acinetobacter baumannii |