Literature summary for 3.1.4.4 extracted from

Driskell, L.O.; Yu, X.J.; Zhang, L.; Liu, Y.; Popov, V.L.; Walker, D.H.; Tucker, A.M.; Wood, D.O.
Directed mutagenesis of the Rickettsia prowazekii pld gene encoding phospholipase D (2009), Infect. Immun., 77, 3244-3248.

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Protein Variants

Protein Variants	Comment	Organism
additional information	construction of a partially deleted pld mutant DELTApldt strain, shows reduced virulence in guinea pigs compared to the wild-type strain, phenotype of infection at high and low doses of wild-type and mutant rickettsiae, overview. Inoculation with the DELTApld mutant at low doses confers effective immune protection against the virulent strain in the guinea pig model	Rickettsia prowazekii

Organism

Organism	UniProt	Comment	Textmining
Rickettsia prowazekii	-	strain Madrid Evir, a virulent revertant of the attenuated Madrid E strain, gene pld	-

Source Tissue

Source Tissue	Comment	Organism	Textmining
additional information	rickettsiae from L929 cells	Rickettsia prowazekii	-

Synonyms

Synonyms	Comment	Organism
PLD	-	Rickettsia prowazekii

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Release 2023.1 (January 2023)