Literature summary for 3.1.4.4 extracted from

Ahn, E.K.; Lim, O.K.; Nam, H.Y.; Kim, H.J.; Chung, N.; Bae, G.N.; Lim, Y.
Silica induced phospholipase D (PLD) activation in Rat2 fibroblasts (2005), J. Toxicol. Public Health, 21, 291-295.

No PubMed abstract available

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Inhibitors

Inhibitors	Comment	Organism	Structure
5,5'-dimethyl-1,2-bis-(2-aminophenoxy)-ethane-N,N,N',N'-tetraacetic acid	partial	Rattus norvegicus
EGTA	partial	Rattus norvegicus
additional information	the silica-induced phospholipase D activity is partially attenuated by the pretreatment with U73122, genistein, PD 98056 and mepacrine	Rattus norvegicus

Organism

Organism	UniProt	Comment	Textmining
Rattus norvegicus	-	-	-

Source Tissue

Source Tissue	Comment	Organism	Textmining
fibroblast	-	Rattus norvegicus	-

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Release 2023.1 (January 2023)