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Literature summary for 3.1.4.4 extracted from
- Phospholipase D (2000), Ann. N. Y. Acad. Sci., 905, 61-68.
Activating Compound
| Activating Compound | Comment | Organism | Structure |
|---|---|---|---|
| additional information | overview on activating compounds and mechanism | Mammalia |
Inhibitors
| Inhibitors | Comment | Organism | Structure |
|---|---|---|---|
| additional information | overview on inhibitory compounds and mechanism | Mammalia |
Localization
| Localization | Comment | Organism | GeneOntology No. | Textmining |
|---|---|---|---|---|
| caveolae | PLD2 | Mammalia | - |
- |
| endoplasmic reticulum | PLD1 | Mammalia | 5783 | - |
| endosome | late endosome, PLD1 | Mammalia | 5768 | - |
| Golgi apparatus | PLD1 | Mammalia | 5794 | - |
| plasma membrane | PLD2 | Mammalia | 5886 | - |
Organism
| Organism | UniProt | Comment | Textmining |
|---|---|---|---|
| Mammalia | - |
isozymes PLD1, PLD2, regulation of enzyme activity | - |
Posttranslational Modification
| Posttranslational Modification | Comment | Organism |
|---|---|---|
| phosphoprotein | PLD1, regulated by protein kinase alpha, beta, gamma, activation in vitro does not require phosphorylation, but tyrosine phosphorylation occurs in vivo, overview | Mammalia |
Reaction
| Reaction | Comment | Organism | Reaction ID |
|---|---|---|---|
| a phosphatidylcholine + H2O = choline + a phosphatidate | mechanism | Mammalia |
aSubunits
| Subunits | Comment | Organism |
|---|---|---|
| More | overview on subunit domains | Mammalia |
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