Any feedback?
Literature summary for 3.1.4.4 extracted from
- Characterization of a rat brain phospholipase D isozyme (1998), J. Biol. Chem., 273, 7044-7051.
Activating Compound
| Activating Compound | Comment | Organism | Structure |
|---|---|---|---|
| ADP-ribosylation factor | GTP dependent activation | Rattus norvegicus | |
| GTP | - |
Rattus norvegicus |  |
| guanosine 5'-3-O-(thio)triphosphate | GTP analog | Rattus norvegicus | |
| phosphatidylinositol 3,4,5-triphosphate | - |
Rattus norvegicus | |
| phosphatidylinositol 4,5-bisphosphate | - |
Rattus norvegicus | |
| Protein kinase C | only phorbolester activated proteinkinase C | Rattus norvegicus | |
| RhoA | small G proteins ARF3 and RhoA in the presence of guanosine 5'-3-O-(thio)triphosphate | Rattus norvegicus | |
Cloned(Commentary)
| Cloned (Comment) | Organism |
|---|---|
| expression in insect SF9 cells | Rattus norvegicus |
Inhibitors
| Inhibitors | Comment | Organism | Structure |
|---|---|---|---|
| Mg2+ | - |
Rattus norvegicus | |
| oleic acid | - |
Rattus norvegicus | |
| Proteinkinase C | phosphorylated and inhibited the enzyme in vitro | Rattus norvegicus |
Metals/Ions
| Metals/Ions | Comment | Organism | Structure |
|---|---|---|---|
| Ca2+ | - |
Rattus norvegicus | |
Natural Substrates/ Products (Substrates)
| Natural Substrates | Organism | Comment (Nat. Sub.) | Natural Products | Comment (Nat. Pro.) | Rev. | Reac. |
|---|---|---|---|---|---|---|
| phospholipid + H2O | Rattus norvegicus | phosphoric ester hydrolysis | phosphatidic acid + alcohol | - |
? | |
Organism
| Organism | UniProt | Comment | Textmining |
|---|---|---|---|
| Rattus norvegicus | - |
- |
- |
Posttranslational Modification
| Posttranslational Modification | Comment | Organism |
|---|---|---|
| glycoprotein | - |
Rattus norvegicus |
Source Tissue
| Source Tissue | Comment | Organism | Textmining |
|---|---|---|---|
| brain | - |
Rattus norvegicus | - |
Substrates and Products (Substrate)
| Substrates | Comment Substrates | Organism | Products | Comment (Products) | Rev. | Reac. |
|---|---|---|---|---|---|---|
| phosphatidylcholine + H2O | - |
Rattus norvegicus | 1,2-diacylglycerophosphate + choline | - |
? | |
| phospholipid + H2O | phosphoric ester hydrolysis | Rattus norvegicus | phosphatidic acid + alcohol | - |
? | |
pH Optimum
| pH Optimum Minimum | pH Optimum Maximum | Comment | Organism |
|---|---|---|---|
| 6.5 | 7.5 | recombinant protein | Rattus norvegicus |
Use of this online version of BRENDA is free under the CC BY 4.0 license. See terms of use for full details.
Release 2023.1 (January 2023)
Legal
Curated at
Member of
