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Literature summary for 3.1.4.4 extracted from

  • Hodgkin, M.N.; Clark, J.M.; Rose, S.; Saqib, K.; Wakelam, M.J.
    Characterization of the regulation of phospholipase D activity in the detergent-insoluble fraction of HL60 cells by protein kinase C and small G-proteins (1999), Biochem. J., 339, 87-93.
    View publication on PubMedView publication on EuropePMC
Search for more literature for 3.1.4.4

Activating Compound

Activating Compound Comment Organism Structure
ADP-ribosylation factor required for activity Homo sapiens
ADP-ribosylation factor GTP dependent activation Homo sapiens
GTP
-
 Homo sapiens
phorbol 12-myristate 13-acetate phorbol ester stimulation involves proteinkinase C but not ADP-ribosylation factor proteins Homo sapiens
Protein kinase C
-
 Homo sapiens
RhoA only in synergy with ARF1 Homo sapiens

Cloned(Commentary)

Cloned (Comment) Organism
expression in Spodoptera frugiperda Homo sapiens

Localization

Localization Comment Organism GeneOntology No. Textmining
membrane detergent insoluble fraction Homo sapiens 16020
-

Natural Substrates/ Products (Substrates)

Natural Substrates Organism Comment (Nat. Sub.) Natural Products Comment (Nat. Pro.) Rev. Reac.
phospholipid + alcohol Homo sapiens transphosphaditylation phospholipid + alcohol
-
 ?
phospholipid + H2O Homo sapiens phosphoric ester hydrolysis phosphatidic acid + alcohol
-
 ?

Organism

Organism UniProt Comment Textmining
Homo sapiens
-
-
-

Source Tissue

Source Tissue Comment Organism Textmining
HL-60 cell human leucemia cell line Homo sapiens
-
placenta
-
 Homo sapiens
-

Substrates and Products (Substrate)

Substrates Comment Substrates Organism Products Comment (Products) Rev. Reac.
phosphatidylcholine + butanol
-
 Homo sapiens phosphatidylbutanol + choline
-
 ?
phosphatidylcholine + H2O
-
 Homo sapiens 1,2-diacylglycerophosphate + choline
-
 ?
phospholipid + alcohol transphosphaditylation Homo sapiens phospholipid + alcohol
-
 ?
phospholipid + H2O phosphoric ester hydrolysis Homo sapiens phosphatidic acid + alcohol
-
 ?