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Literature summary for 3.1.4.38 extracted from

  • Sok D.E.; Kim, M.R.
    Characterization of a Zn(2+)-requiring glycerophosphocholine cholinephosphodiesterase possessing p-nitrophenylphosphocholine phosphodiesterase activity (1992), Biochem. J., 286, 435-440.
    View publication on PubMedView publication on EuropePMC
Search for more literature for 3.1.4.38

Inhibitors

Inhibitors Comment Organism Structure
EDTA no enzyme activity with prior incubation Mus musculus

KM Value [mM]

KM Value [mM] KM Value Maximum [mM] Substrate Comment Organism Structure
0.0055
-
 p-nitrophenylphosphocholine Zn2+ is required for maximum activity Mus musculus
0.048
-
 sn-glycero-3-phosphocholine
-
 Mus musculus

Localization

Localization Comment Organism GeneOntology No. Textmining
membrane
-
 Mus musculus 16020
-

Metals/Ions

Metals/Ions Comment Organism Structure
Zn2+ Zn2+ is required for maximum activity Mus musculus

Molecular Weight [Da]

Molecular Weight [Da] Molecular Weight Maximum [Da] Comment Organism
74000
-
 SDS-PAGE Mus musculus
75000
-
 gel filtration Mus musculus

Organism

Organism UniProt Comment Textmining
Mus musculus
-
-
-

Purification (Commentary)

Purification (Comment) Organism
-
 Mus musculus

Source Tissue

Source Tissue Comment Organism Textmining
brain
-
 Mus musculus
-

Substrates and Products (Substrate)

Substrates Comment Substrates Organism Products Comment (Products) Rev. Reac.
p-nitrophenylphosphocholine + H2O
-
 Mus musculus p-nitrophenol + choline phosphate
-
 r
sn-glycero-3-phosphocholine + H2O
-
 Mus musculus glycerol + choline phosphate
-
 r

Temperature Stability [°C]

Temperature Stability Minimum [°C] Temperature Stability Maximum [°C] Comment Organism
35 50 90% loss of activity at 50oC Mus musculus

pH Optimum

pH Optimum Minimum pH Optimum Maximum Comment Organism
10.5
-
-
 Mus musculus

pH Range

pH Minimum pH Maximum Comment Organism
9 11
-
 Mus musculus