Crystallization (Comment) | Organism |
---|---|
structure of ENPP6 in complex with phosphocholine. The choline moiety of the phosphocholine is recognized by a choline-binding pocket formed by conserved aromatic and acidic residues | Mus musculus |
Natural Substrates | Organism | Comment (Nat. Sub.) | Natural Products | Comment (Nat. Pro.) | Rev. | Reac. |
---|---|---|---|---|---|---|
sn-glycero-3-phosphocholine + H2O | Mus musculus | the choline moiety of glycero-3-phosphocholine is incorporated into phosphocholine in an ENPP6-dependent manner both in vivo and in vitro | glycerol + phosphocholine | - |
? |
Organism | UniProt | Comment | Textmining |
---|---|---|---|
Mus musculus | Q8BGN3 | - |
- |
Source Tissue | Comment | Organism | Textmining |
---|---|---|---|
liver | high expression in liver sinusoidal endothelial cells | Mus musculus | - |
oligodendrocyte | high expression | Mus musculus | - |
Substrates | Comment Substrates | Organism | Products | Comment (Products) | Rev. | Reac. |
---|---|---|---|---|---|---|
sn-glycero-3-phosphocholine + H2O | - |
Mus musculus | glycerol + phosphocholine | - |
? | |
sn-glycero-3-phosphocholine + H2O | the choline moiety of glycero-3-phosphocholine is incorporated into phosphocholine in an ENPP6-dependent manner both in vivo and in vitro | Mus musculus | glycerol + phosphocholine | - |
? |
Synonyms | Comment | Organism |
---|---|---|
ectonucleotide pyrophosphatase/phosphodiesterase family member 6 | - |
Mus musculus |
ENPP6 | - |
Mus musculus |
General Information | Comment | Organism |
---|---|---|
physiological function | ENPP6-deficient mice exhibit fatty liver and hypomyelination | Mus musculus |