Literature summary for 3.1.4.35 extracted from

Cote, R.H.
Kinetics and regulation of cGMP binding to noncatalytic binding sites on photoreceptor phosphodiesterase (2000), Methods Enzymol., 315, 646-672.

Search for more literature for 3.1.4.35

Activating Compound

Activating Compound	Comment	Organism	Structure
Transducin	heterotrimeric G protein	Rana sp.

Inhibitors

Inhibitors	Comment	Organism	Structure
inhibitory gamma subunit of PDE	i.e. Pgamma	Rana sp.

Natural Substrates/ Products (Substrates)

Natural Substrates	Organism	Comment (Nat. Sub.)	Natural Products	Comment (Nat. Pro.)	Rev.	Reac.
guanosine 3',5'-cyclic phosphate + H2O	Rana sp.	-	guanosine 5'-phosphate	-	?

Organism

Organism	UniProt	Comment	Textmining
Rana sp.	-	frog	-

Source Tissue

Source Tissue	Comment	Organism	Textmining
photoreceptor	outer segments of rod and cone photoreceptors	Rana sp.	-

Substrates and Products (Substrate)

Substrates	Comment Substrates	Organism	Products	Comment (Products)	Rev.	Reac.
guanosine 3',5'-cyclic phosphate + H2O	-	Rana sp.	guanosine 5'-phosphate	-	?

Subunits

Subunits	Comment	Organism
?	PDE holoenzyme consists of a catalytic dimer Palpa,beta to which the inhibitory Pgamma subunits bind	Rana sp.

Synonyms

Synonyms	Comment	Organism
PDE6	-	Rana sp.

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Release 2023.1 (January 2023)