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Literature summary for 3.1.4.3 extracted from

  • Fiester, S.E.; Arivett, B.A.; Schmidt, R.E.; Beckett, A.C.; Ticak, T.; Carrier, M.V.; Ghosh, R.; Ohneck, E.J.; Metz, M.L.; Sellin Jeffries, M.K.; Actis, L.A.
    Iron-regulated phospholipase C activity contributes to the cytolytic activity and virulence of Acinetobacter baumannii (2016), PLoS ONE, 11, e0167068 .
    View publication on PubMedView publication on EuropePMC
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Natural Substrates/ Products (Substrates)

Natural Substrates Organism Comment (Nat. Sub.) Natural Products Comment (Nat. Pro.) Rev. Reac.
phosphatidylcholine + H2O Acinetobacter baumannii
-
 1,2-diacyl-sn-glycerol + phosphorylcholine
-
 ?
phosphatidylcholine + H2O Acinetobacter baumannii ATCC 19606T
-
 1,2-diacyl-sn-glycerol + phosphorylcholine
-
 ?

Organism

Organism UniProt Comment Textmining
Acinetobacter baumannii
-
-
-
Acinetobacter baumannii ATCC 19606T
-
-
-

Substrates and Products (Substrate)

Substrates Comment Substrates Organism Products Comment (Products) Rev. Reac.
phosphatidylcholine + H2O
-
 Acinetobacter baumannii 1,2-diacyl-sn-glycerol + phosphorylcholine
-
 ?
phosphatidylcholine + H2O
-
 Acinetobacter baumannii ATCC 19606T 1,2-diacyl-sn-glycerol + phosphorylcholine
-
 ?

Synonyms

Synonyms Comment Organism
PC-PLC
-
 Acinetobacter baumannii
phosphatidylcholine-specific phospholipase C
-
 Acinetobacter baumannii
PLC1
-
 Acinetobacter baumannii
PLC2
-
 Acinetobacter baumannii

General Information

General Information Comment Organism
physiological function isoforms PLC1 and PLC2 play a concerted role in hemolytic and cytolytic activities although isoform PLC1 plays a more critical role in the virulence of Acinetobacter baumannii Acinetobacter baumannii