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Literature summary for 3.1.4.3 extracted from

  • Zhao, J.; Zhao, B.; Wang, W.; Huang, B.; Zhang, S.; Miao, J.
    Phosphatidylcholine-specific phospholipase C and ROS were involved in chicken blastodisc differentiation to vascular endothelial cells (2007), J. Cell. Biochem., 102, 421-428.
    View publication on PubMed
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Inhibitors

Inhibitors Comment Organism Structure
D609 i.e. tricyclodecan-9-yl potassium xanthate, inhibition of isoform PC-PLC. After application on blastodisc at 24 h, cell differentiation cannot progress and intracellular level of reactive oxygen species is elevated Gallus gallus

Natural Substrates/ Products (Substrates)

Natural Substrates Organism Comment (Nat. Sub.) Natural Products Comment (Nat. Pro.) Rev. Reac.
additional information Gallus gallus isoform PC-PLC and reactive oxygen species are involved in chicken blastodisc differentiation to vascular endothelial cells ?
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Organism

Organism UniProt Comment Textmining
Gallus gallus
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Source Tissue

Source Tissue Comment Organism Textmining
blastodisc in vitro vasculogenesis model. Activities of both Ca2+-dependent and independent isoform PC-PLC and the level of reactive oxygen species are elevated during the endothelial differentiation of the blastodisc. Ca2+-independent PC-PLC undergoes an increase in 24 h, then decreases gradually with the cell differentiation, while Ca2+-dependent PC-PLC is almost not changed during the process Gallus gallus
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Substrates and Products (Substrate)

Substrates Comment Substrates Organism Products Comment (Products) Rev. Reac.
additional information isoform PC-PLC and reactive oxygen species are involved in chicken blastodisc differentiation to vascular endothelial cells Gallus gallus ?
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 ?