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Literature summary for 3.1.4.3 extracted from

  • Wang, N.; Sun, C.; Huo, S.; Zhang, Y.; Zhao, J.; Zhang, S.; Miao, J.
    Cooperation of phosphatidylcholine-specific phospholipase C and basic fibroblast growth factor in the neural differentiation of mesenchymal stem cells in vitro (2008), Int. J. Biochem. Cell Biol., 40, 294-306.
    View publication on PubMed
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Inhibitors

Inhibitors Comment Organism Structure
D609
-
 Rattus norvegicus

Natural Substrates/ Products (Substrates)

Natural Substrates Organism Comment (Nat. Sub.) Natural Products Comment (Nat. Pro.) Rev. Reac.
additional information Rattus norvegicus low isoform PC-PLC activity is required for mesenchymal stem cell neuronal differentiation, and basic fibroblast growth factor is necessary for maintaining the neuronal differentiation state ?
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 ?

Organism

Organism UniProt Comment Textmining
Rattus norvegicus
-
-
-

Source Tissue

Source Tissue Comment Organism Textmining
mesenchymal stem cell suppression of isoform PC-PLC in presence of basic fibroblast growth factor can induce neuronal differentiation accompanied by increase in viability of differentiated cells. The resting membrane potential of the differentiated cells gradually decreases, but the mitochondrial membrane potential rises with increasing inhibition time Rattus norvegicus
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Substrates and Products (Substrate)

Substrates Comment Substrates Organism Products Comment (Products) Rev. Reac.
additional information low isoform PC-PLC activity is required for mesenchymal stem cell neuronal differentiation, and basic fibroblast growth factor is necessary for maintaining the neuronal differentiation state Rattus norvegicus ?
-
 ?