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Literature summary for 3.1.4.3 extracted from

  • Alvarez-Breckenridge, C.A.; Waite, K.A.; Eng, C.
    PTEN regulates phospholipase D and phospholipase C (2007), Hum. Mol. Genet., 16, 1157-1163.
    View publication on PubMed

Application

Application Comment Organism
medicine tumor suppressor PTEN is involved in both phospholipase C and phospholipase D activation pathways. Pathogenesis of Cowden syndrome and Bannayan-Riley-Ruvalcaba syndrome has further aspects beyond activating the PI3K pathway Homo sapiens

Organism

Organism UniProt Comment Textmining
Homo sapiens
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-
-

Source Tissue

Source Tissue Comment Organism Textmining
MCF-7 cell
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Homo sapiens
-