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Literature summary for 3.1.4.3 extracted from

  • Lee, C.W.; Lee, K.H.; Rhee, S.G.
    Characterization of phospholipase C isoenzymes in bovine retina: Purification of phospholipase C-beta 4 (1994), Methods Enzymol., 238, 227-237.
    View publication on PubMed

Molecular Weight [Da]

Molecular Weight [Da] Molecular Weight Maximum [Da] Comment Organism
85000
-
PLC delta 1 and PLC delta 2 Bos taurus
100000
-
PLC beta 1 isoform Bos taurus
130000
-
PLC beta 4, isoforms with slightly different MW exist Bos taurus
140000
-
PLC beta 1 isoform Bos taurus
145000
-
PLC gamma 1 Bos taurus
150000
-
PLC beta 1 isoform Bos taurus
152000
-
PLC beta 3 Bos taurus

Natural Substrates/ Products (Substrates)

Natural Substrates Organism Comment (Nat. Sub.) Natural Products Comment (Nat. Pro.) Rev. Reac.
phosphatidylinositol-bisphosphate + H2O Bos taurus
-
inositol 1,4,5-trisphosphate + 1,2-diacylglycerol
-
?

Organism

Organism UniProt Comment Textmining
Bos taurus
-
cow
-

Purification (Commentary)

Purification (Comment) Organism
column chromatography, ion-exchange chromatography Bos taurus

Source Tissue

Source Tissue Comment Organism Textmining
retina
-
Bos taurus
-

Storage Stability

Storage Stability Organism
-70°C Bos taurus

Substrates and Products (Substrate)

Substrates Comment Substrates Organism Products Comment (Products) Rev. Reac.
phosphatidylinositol + H2O
-
Bos taurus inositol monophosphate + diacylglycerol
-
?
phosphatidylinositol-bisphosphate + H2O
-
Bos taurus inositol 1,4,5-trisphosphate + 1,2-diacylglycerol
-
?