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Literature summary for 3.1.4.2 extracted from

  • Lloyd-Davies, K.A.; Michell, R.H.; Coleman, R.
    Glycerylphosphorylcholine phosphodiesterase in rat liver (1972), Biochem. J., 127, 357-368.
    View publication on PubMedView publication on EuropePMC
Search for more literature for 3.1.4.2

Inhibitors

Inhibitors Comment Organism Structure
EDTA complete inhibition at 1 mM Rattus sp.
EGTA complete inhibition at 1 mM Rattus sp.

KM Value [mM]

KM Value [mM] KM Value Maximum [mM] Substrate Comment Organism Structure
0.95
-
 sn-glycero 3-phosphocholine
-
 Rattus sp.

Localization

Localization Comment Organism GeneOntology No. Textmining
cytosol
-
 Rattus sp. 5829
-
lysosome
-
 Rattus sp. 5764
-
microsome
-
 Rattus sp.
-
-
nucleus
-
 Rattus sp. 5634
-
plasma membrane
-
 Rattus sp. 5886
-

Metals/Ions

Metals/Ions Comment Organism Structure
Ca2+ fully restored activity if chelating agents used Rattus sp.
Cu2+ activity restored if chelating agents used Rattus sp.
Mg2+ activity restored if chelating agents used Rattus sp.
Ni2+ restore activity if EDTA or EGTA used Rattus sp.

Natural Substrates/ Products (Substrates)

Natural Substrates Organism Comment (Nat. Sub.) Natural Products Comment (Nat. Pro.) Rev. Reac.
sn-glycero 3-phosphorylcholine + H2O Rattus sp. cellular phosphatidylcholine catabolic pathway ?
-
 ?

Organism

Organism UniProt Comment Textmining
Rattus sp.
-
-
-

Purification (Commentary)

Purification (Comment) Organism
partial Rattus sp.

Source Tissue

Source Tissue Comment Organism Textmining
liver
-
 Rattus sp.
-

Substrates and Products (Substrate)

Substrates Comment Substrates Organism Products Comment (Products) Rev. Reac.
sn-glycero 3-phosphorylcholine + H2O
-
 Rattus sp. sn-glycerol 3-phosphate + choline
-
 ?
sn-glycero 3-phosphorylcholine + H2O cellular phosphatidylcholine catabolic pathway Rattus sp. ?
-
 ?

pH Optimum

pH Optimum Minimum pH Optimum Maximum Comment Organism
8.5 9
-
 Rattus sp.