Any feedback?
Literature summary for 3.1.4.2 extracted from
- Characterization of glycerophosphocholine phosphodiesterase activity and phosphatidylcholine biosynthesis in cultured retinal microcapillary pericytes. Effect of adenosine and endothelin-1 (2003), Lipids, 38, 45-52.
Activating Compound
| Activating Compound | Comment | Organism | Structure |
|---|---|---|---|
| Ca2+ | - |
Bos taurus |  |
| Cu2+ | - |
Bos taurus | |
| Mg2+ | - |
Bos taurus | |
| Zn2+ | - |
Bos taurus | |
Inhibitors
| Inhibitors | Comment | Organism | Structure |
|---|---|---|---|
| EDTA | at 1 mM, about 85% inhibition | Bos taurus | |
| N-ethylmaleimide | at 3 mM, about 30% inhibition | Bos taurus | |
| p-chloromercuribenzoate | at 0.1 mM, about 25% inhibition | Bos taurus | |
KM Value [mM]
| KM Value [mM] | KM Value Maximum [mM] | Substrate | Comment | Organism | Structure |
|---|---|---|---|---|---|
| 0.31 | - |
sn-glycero 3-phosphorylcholine | pH 8.0, 37°C | Bos taurus | |
Localization
| Localization | Comment | Organism | GeneOntology No. | Textmining |
|---|---|---|---|---|
| microsome | minority of enzymic activity | Bos taurus | - |
- |
| plasma membrane | majority of enzymic activity | Bos taurus | 5886 | - |
Natural Substrates/ Products (Substrates)
| Natural Substrates | Organism | Comment (Nat. Sub.) | Natural Products | Comment (Nat. Pro.) | Rev. | Reac. |
|---|---|---|---|---|---|---|
| additional information | Bos taurus | physiological role of enzyme | ? | - |
? | |
Organism
| Organism | UniProt | Comment | Textmining |
|---|---|---|---|
| Bos taurus | - |
- |
- |
Source Tissue
| Source Tissue | Comment | Organism | Textmining |
|---|---|---|---|
| brain | medium enzymic activity | Bos taurus | - |
| kidney | renal epithelial cell culture, low enzymic activity | Bos taurus | - |
| liver | medium enzymic activity | Bos taurus | - |
| retina | cultured retinal microcapillary pericytes, high enzymic activity | Bos taurus | - |
Substrates and Products (Substrate)
| Substrates | Comment Substrates | Organism | Products | Comment (Products) | Rev. | Reac. |
|---|---|---|---|---|---|---|
| additional information | physiological role of enzyme | Bos taurus | ? | - |
? | |
| sn-glycero 3-phosphorylcholine + H2O | - |
Bos taurus | sn-glycerol 3-phosphate + choline | - |
? | |
pH Optimum
| pH Optimum Minimum | pH Optimum Maximum | Comment | Organism |
|---|---|---|---|
| 8.5 | - |
- |
Bos taurus |
Use of this online version of BRENDA is free under the CC BY 4.0 license. See terms of use for full details.
Release 2023.1 (January 2023)
Legal
Curated at
Member of
