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Literature summary for 3.1.4.17 extracted from

  • Leroy, M.J.; Degerman, E.; Taira, M.; Murata, T.; Wang, L.H.; Movsesian, M.A.; Meacci, E.; Manganiello, V.C.
    Characterization of two recombinant PDE3 (cGMP inhibited cyclic nucleotide phosphodiesterase) isoforms, RcGIP1 and HcGIP2, expressed in NIH 3006 murine fibroblasts and Sf9 insect cells (1996), Biochemistry, 35, 10194-10202.
    View publication on PubMed
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Cloned(Commentary)

Cloned (Comment) Organism
expression in NIH3006 murine fibroblasts and baculovirus-infected Sf9 insect cells Homo sapiens
expression in NIH3006 murine fibroblasts and Sf9 insect cells Rattus norvegicus

Inhibitors

Inhibitors Comment Organism Structure
cGMP
-
 Homo sapiens
cGMP
-
 Rattus norvegicus

Organism

Organism UniProt Comment Textmining
Homo sapiens
-
-
-
Rattus norvegicus
-
-
-

Substrates and Products (Substrate)

Substrates Comment Substrates Organism Products Comment (Products) Rev. Reac.
3',5'-cAMP + H2O
-
 Homo sapiens 5'-AMP
-
 ?
3',5'-cAMP + H2O
-
 Rattus norvegicus 5'-AMP
-
 ?
nucleoside 3',5'-cyclic phosphate + H2O
-
 Homo sapiens nucleoside 5'-phosphate
-
 ?
nucleoside 3',5'-cyclic phosphate + H2O
-
 Rattus norvegicus nucleoside 5'-phosphate
-
 ?