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Literature summary for 3.1.4.17 extracted from

  • Ryan, J.A.; Toscano, W.A.
    Multiple forms of cyclic nucleotide phosphodiesterase in a murine adrenal cortex cell line (Y-1) (1985), Arch. Biochem. Biophys., 241, 403-412.
    View publication on PubMed
Search for more literature for 3.1.4.17

Inhibitors

Inhibitors Comment Organism Structure
Calmidazolium soluble but not particulate form Mus musculus
cAMP particulate enzyme Mus musculus
Chloropromazine soluble but not particulate form Mus musculus
ethylene glycol bis(beta-aminoethyl ether)-N,N'-tetraacetic acid soluble but not particulate form Mus musculus
N-(6-Aminohexyl)-5-chloro-1-naphthalenesulfonamide soluble but not particulate form Mus musculus

KM Value [mM]

KM Value [mM] KM Value Maximum [mM] Substrate Comment Organism Structure
0.03
-
 3',5'-cGMP soluble enzyme Mus musculus
0.09
-
 3',5'-cAMP particulate enzyme Mus musculus
0.1
-
 3',5'-cGMP particulate enzyme Mus musculus
0.125
-
 3',5'-cAMP soluble enzyme Mus musculus

Metals/Ions

Metals/Ions Comment Organism Structure
Ca2+ Ca2+/calmodulin stimulated Mus musculus

Organism

Organism UniProt Comment Textmining
Mus musculus
-
-
-

Purification (Commentary)

Purification (Comment) Organism
540fold Mus musculus

Source Tissue

Source Tissue Comment Organism Textmining
Y-1 cell
-
 Mus musculus
-

Substrates and Products (Substrate)

Substrates Comment Substrates Organism Products Comment (Products) Rev. Reac.
3',5'-cAMP + H2O
-
 Mus musculus 5'-AMP
-
 ?
3',5'-cGMP + H2O
-
 Mus musculus 5'-GMP
-
 ?
nucleoside 3',5'-cyclic phosphate + H2O
-
 Mus musculus nucleoside 5'-phosphate
-
 ?