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Literature summary for 3.1.4.11 extracted from

  • Thore, S.; Dyachok, O.; Tengholm, A.
    Oscillations of phospholipase C activity triggered by depolarization and Ca2+ influx in insulin-secreting cells (2004), J. Biol. Chem., 279, 19396-19400.
    View publication on PubMed
Search for more literature for 3.1.4.11

Localization

Localization Comment Organism GeneOntology No. Textmining
plasma membrane activation of PLC by muscarinic acid or purinergic receptor stimulation results in translocation from the plasma membrane to the cytoplasm Rattus norvegicus 5886
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Metals/Ions

Metals/Ions Comment Organism Structure
Ca2+ required Rattus norvegicus

Natural Substrates/ Products (Substrates)

Natural Substrates Organism Comment (Nat. Sub.) Natural Products Comment (Nat. Pro.) Rev. Reac.
additional information Rattus norvegicus PLC activity is under tight dynamic control of the Ca2+ concentration. In insulin-secreting beta-cells, this mechanism provides a link between Ca2+ influx and release from intracellular stores that may be important in the regulation of insulin secretion ?
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Organism

Organism UniProt Comment Textmining
Rattus norvegicus
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Source Tissue

Source Tissue Comment Organism Textmining
INS-1 cell
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 Rattus norvegicus
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Substrates and Products (Substrate)

Substrates Comment Substrates Organism Products Comment (Products) Rev. Reac.
additional information PLC activity is under tight dynamic control of the Ca2+ concentration. In insulin-secreting beta-cells, this mechanism provides a link between Ca2+ influx and release from intracellular stores that may be important in the regulation of insulin secretion Rattus norvegicus ?
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 ?

Synonyms

Synonyms Comment Organism
PLCdeta1
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 Rattus norvegicus