Activating Compound | Comment | Organism | Structure |
---|---|---|---|
deoxycholate | - |
Rattus norvegicus | |
additional information | sodium lauryl sulfate, tetradecyl-trimethylammonium bromide, and Triton X-100 do not activate phosphatidylinositol phosphodiesterase in the presence of Ca2+ | Rattus norvegicus |
Inhibitors | Comment | Organism | Structure |
---|---|---|---|
ATP | 1-5 mM | Rattus norvegicus | |
HgCl2 | - |
Rattus norvegicus |
Localization | Comment | Organism | GeneOntology No. | Textmining |
---|---|---|---|---|
membrane | associated | Rattus norvegicus | 16020 | - |
Metals/Ions | Comment | Organism | Structure |
---|---|---|---|
Ca2+ | stimulates | Rattus norvegicus | |
Mg2+ | stimulates | Rattus norvegicus | |
Mn2+ | stimulates | Rattus norvegicus | |
additional information | Ba2+, Zn2+, Hg2+, K+ are ineffective | Rattus norvegicus | |
additional information | certain divalent cations are necessary for enzyme activity | Rattus norvegicus |
Organism | UniProt | Comment | Textmining |
---|---|---|---|
Rattus norvegicus | - |
- |
- |
Source Tissue | Comment | Organism | Textmining |
---|---|---|---|
kidney | - |
Rattus norvegicus | - |
Substrates | Comment Substrates | Organism | Products | Comment (Products) | Rev. | Reac. |
---|---|---|---|---|---|---|
phosphatidylinositol + H2O | enzyme is specific for phosphatidylinositol | Rattus norvegicus | diacylglycerol + 1D-myo-inositol 1-phosphate | - |
? |
Synonyms | Comment | Organism |
---|---|---|
phosphatidylinositol phosphodiesterase | - |
Rattus norvegicus |
pH Optimum Minimum | pH Optimum Maximum | Comment | Organism |
---|---|---|---|
7 | 8.5 | - |
Rattus norvegicus |
pH Minimum | pH Maximum | Comment | Organism |
---|---|---|---|
6 | 11 | pH: 6.0: about 10% of maximal activity, pH 11.0: about 40% of maximal activity | Rattus norvegicus |