General Stability | Organism |
---|---|
PC-1, nucleotide pyrophosphatase/phosphodiesterase I, divalent cations protect from thermal inactivation | Rattus norvegicus |
Inhibitors | Comment | Organism | Structure |
---|---|---|---|
EDTA | PC-1, nucleotide pyrophosphatase/phosphodiesterase I: glycine-enhanced inhibition, reversed by Mg2+ | Rattus norvegicus | |
glycine | PC-1, nucleotide pyrophosphatase/phosphodiesterase I: at high concentrations, 100 mM; PC-1, nucleotide pyrophosphatase/phosphodiesterase I: glycine-enhanced inhibition by EDTA, by itself, up to 25 mM, is not inhibitory | Rattus norvegicus |
Organism | UniProt | Comment | Textmining |
---|---|---|---|
Rattus norvegicus | - |
PC-1, nucleotide pyrophosphatase/phosphodiesterase I | - |
Purification (Comment) | Organism |
---|---|
PC-1, NPP/PDE, nucleotide pyrophosphatase/phosphodiesterase I | Rattus norvegicus |
Source Tissue | Comment | Organism | Textmining |
---|---|---|---|
liver | PC-1, nucleotide pyrophosphatase/phosphodiesterase I | Rattus norvegicus | - |
Specific Activity Minimum [µmol/min/mg] | Specific Activity Maximum [µmol/min/mg] | Comment | Organism |
---|---|---|---|
13 | - |
nucleotide pyrophosphatase/phosphodiesterase I | Rattus norvegicus |
Storage Stability | Organism |
---|---|
nucleotide pyrophosphatase/phosphodiesterase I, -20øC, 1 mg/ml bovine serum albumin, stable for at least 1 year | Rattus norvegicus |
nucleotide pyrophosphatase/phosphodiesterase I, once thawed, 4øC, 1 mg/ml bovine serum albumin, stable for at least 1 month | Rattus norvegicus |
Substrates | Comment Substrates | Organism | Products | Comment (Products) | Rev. | Reac. |
---|---|---|---|---|---|---|
5'-p-nitrophenyl deoxythymidine 5'-phosphate + H2O | nucleotide pyrophosphatase/phosphodiesterase I | Rattus norvegicus | 5'-dTMP + p-nitrophenol | - |
? |
Synonyms | Comment | Organism |
---|---|---|
NPP/PDE | nucleotide pyrophosphatase/phosphodiesterase I | Rattus norvegicus |
nucleotide pyrophosphatase/phosphodiesterase I | EC 3.6.1.9 /EC 3.1.4.1 | Rattus norvegicus |
PC-1 | PC-1, plasma-cell differentiation antigen-1, membrane glycoprotein, has 5'-nucleotide phosphodiesterase and nucleotide pyrophosphatase activity | Rattus norvegicus |
Temperature Stability Minimum [°C] | Temperature Stability Maximum [°C] | Comment | Organism |
---|---|---|---|
additional information | - |
PC-1, nucleotide pyrophosphatase/phosphodiesterase I: EDTA favors thermal inactivation, divalent cations protect from thermal inactivation | Rattus norvegicus |
pH Optimum Minimum | pH Optimum Maximum | Comment | Organism |
---|---|---|---|
9 | 9.1 | nucleotide pyrophosphatase/phosphodiesterase I | Rattus norvegicus |