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Literature summary for 3.1.4.1 extracted from

  • Hawley, D.M.; Schulz, A.R.; Hodes, M.E.
    A comparative kinetic analysis of six substrates widely used for the detection and quantitation of phosphodiesterase I (1984), Enzyme, 32, 105-109.
    View publication on PubMed
Search for more literature for 3.1.4.1

KM Value [mM]

KM Value [mM] KM Value Maximum [mM] Substrate Comment Organism Structure
0.7
-
 p-nitrophenylthymidine 5'-phosphate
-
 Bos taurus
0.8
-
 bis(4-methylumbelliferyl) phosphate
-
 Bos taurus
1.6
-
 bis(p-nitrophenyl) phosphate
-
 Bos taurus
2
-
 4-methylumbelliferyl thymidine 5'-phosphate
-
 Bos taurus
4.9
-
 4-methylumbelliferyl phenylphosphonate
-
 Bos taurus
15
-
 p-Nitrophenyl phenylphosphonate
-
 Bos taurus

Organism

Organism UniProt Comment Textmining
Bos taurus
-
-
-

Source Tissue

Source Tissue Comment Organism Textmining
intestine
-
 Bos taurus
-

Substrates and Products (Substrate)

Substrates Comment Substrates Organism Products Comment (Products) Rev. Reac.
4-methylumbelliferyl phenylphosphonate + H2O
-
 Bos taurus 4-methylumbelliferone + phenylphosphonic acid
-
 ?
4-methylumbelliferyl thymidine 5'-phosphate + H2O
-
 Bos taurus 4-methylumbelliferone + 5'-TMP
-
 ?
bis(4-methylumbelliferyl) phosphate + H2O
-
 Bos taurus ?
-
 ?
bis(p-nitrophenyl) phosphate + H2O
-
 Bos taurus ?
-
 ?
additional information new definition for PDE I activity which takes into account its ability to hydrolyze several types of substrates Bos taurus ?
-
 ?
p-nitrophenyl phenylphosphonate + H2O
-
 Bos taurus p-nitrophenol + benzenephosphonic acid
-
 ?
p-nitrophenylthymidine 5'-phosphate + H2O
-
 Bos taurus 5'-TMP + p-nitrophenol
-
 ?

Synonyms

Synonyms Comment Organism
PDE I
-
 Bos taurus