Literature summary for 3.1.30.1 extracted from

Silber, J.R.; Loeb, L.A.
S1 nuclease does not cleave DNA at single-base mis-matches (1981), Biochim. Biophys. Acta, 656, 256-264.

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Natural Substrates/ Products (Substrates)

Natural Substrates	Organism	Comment (Nat. Sub.)	Natural Products	Comment (Nat. Pro.)	Rev.	Reac.
DNA + H2O	Neurospora crassa	-	5'-phosphomononucleotides + 5'-phosphooligonucleotides	-	?
DNA + H2O	Aspergillus oryzae	-	5'-phosphomononucleotides + 5'-phosphooligonucleotides	-	?

Organism

Organism	UniProt	Comment	Textmining
Aspergillus oryzae	-	-	-
Neurospora crassa	-	-	-

Substrates and Products (Substrate)

Substrates	Comment Substrates	Organism	Products	Comment (Products)	Rev.	Reac.
DNA + H2O	-	Neurospora crassa	5'-phosphomononucleotides + 5'-phosphooligonucleotides	-	?
DNA + H2O	-	Aspergillus oryzae	5'-phosphomononucleotides + 5'-phosphooligonucleotides	-	?
ssDNA + H2O	no cleavage at single-base mismatches	Neurospora crassa	5'-phosphomononucleotides + 5'-phosphooligonucleotides	-	?
ssDNA + H2O	no cleavage at single-base mismatches	Aspergillus oryzae	5'-phosphomononucleotides + 5'-phosphooligonucleotides	-	?

Synonyms

Synonyms	Comment	Organism
S1 nuclease	-	Aspergillus oryzae

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Release 2023.1 (January 2023)