Literature summary for 3.1.3.B4 extracted from

Del Bel, L.M.; Griffiths, N.; Wilk, R.; Wei, H.C.; Blagoveshchenskaya, A.; Burgess, J.; Polevoy, G.; Price, J.V.; Mayinger, P.; Brill, J.A.
The phosphoinositide phosphatase Sac1 regulates cell shape and microtubule stability in the developing Drosophila eye (2018), Development, 145, 151571 .

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Cloned(Commentary)

Cloned (Comment)	Organism
expressed in HeLa cells	Drosophila melanogaster

Natural Substrates/ Products (Substrates)

Natural Substrates	Organism	Comment (Nat. Sub.)	Natural Products	Comment (Nat. Pro.)	Rev.	Reac.
phosphatidylinositol 4-phosphate + H2O	Drosophila melanogaster	-	phosphatidylinositol + phosphate	-	?

Organism

Organism	UniProt	Comment	Textmining
Drosophila melanogaster	-	-	-

Source Tissue

Source Tissue	Comment	Organism	Textmining
eye	-	Drosophila melanogaster	-

Substrates and Products (Substrate)

Substrates	Comment Substrates	Organism	Products	Comment (Products)	Rev.	Reac.
phosphatidylinositol 4-phosphate + H2O	-	Drosophila melanogaster	phosphatidylinositol + phosphate	-	?

Synonyms

Synonyms	Comment	Organism
phosphoinositide phosphatase	-	Drosophila melanogaster
PI4P phosphatase	-	Drosophila melanogaster
Sac1	-	Drosophila melanogaster

General Information

General Information	Comment	Organism
physiological function	the enzyme is crucial for normal eye development and required for promoting microtubule stability	Drosophila melanogaster

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Release 2023.1 (January 2023)