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Literature summary for 3.1.3.95 extracted from

  • Bong, S.M.; Yang, S.W.; Choi, J.W.; Kim, S.J.; Lee, B.I.
    Crystallization and preliminary X-ray crystallographic analysis of human myotubularin-related protein 1 (2015), Acta Crystallogr. Sect. F, 71, 261-265 .
    View publication on PubMedView publication on EuropePMC
Search for more literature for 3.1.3.95

Cloned(Commentary)

Cloned (Comment) Organism
expressed in Escherichia coli Rosetta2 (DE3) cells Homo sapiens

Crystallization (Commentary)

Crystallization (Comment) Organism
sitting drop vapor diffusion method, using 100 mM Na HEPES pH 7.0, 15% (w/v) polyethylene glycol 20000 Homo sapiens

Molecular Weight [Da]

Molecular Weight [Da] Molecular Weight Maximum [Da] Comment Organism
69000
-
 dynamic light-scattering Homo sapiens

Natural Substrates/ Products (Substrates)

Natural Substrates Organism Comment (Nat. Sub.) Natural Products Comment (Nat. Pro.) Rev. Reac.
1-phosphatidyl-1D-myo-inositol 3,5-bisphosphate + H2O Homo sapiens
-
 1-phosphatidyl-1D-myo-inositol 5-phosphate + phosphate
-
 ?
1-phosphatidyl-1D-myo-inositol 3-phosphate + H2O Homo sapiens
-
 1-phosphatidyl-1D-myo-inositol + phosphate
-
 ?

Organism

Organism UniProt Comment Textmining
Homo sapiens
-
-
-

Purification (Commentary)

Purification (Comment) Organism
Ni-NTA agarose resin column chromatography and Superdex 200 gel filtration Homo sapiens

Substrates and Products (Substrate)

Substrates Comment Substrates Organism Products Comment (Products) Rev. Reac.
1-phosphatidyl-1D-myo-inositol 3,5-bisphosphate + H2O
-
 Homo sapiens 1-phosphatidyl-1D-myo-inositol 5-phosphate + phosphate
-
 ?
1-phosphatidyl-1D-myo-inositol 3-phosphate + H2O
-
 Homo sapiens 1-phosphatidyl-1D-myo-inositol + phosphate
-
 ?

Subunits

Subunits Comment Organism
monomer 1 * 50000, His-tagged enzyme, SDS-PAGE Homo sapiens

Synonyms

Synonyms Comment Organism
MTMR1
-
 Homo sapiens
myotubularin-related protein 1
-
 Homo sapiens