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Literature summary for 3.1.3.94 extracted from
- Brain inositol monophosphatase identified as a galactose 1-phosphatase (1997), Brain Res., 778, 99-106.
Cloned(Commentary)
| Cloned (Comment) | Organism |
|---|---|
| expression in Escherichia coli | Homo sapiens |
Inhibitors
| Inhibitors | Comment | Organism | Structure |
|---|---|---|---|
| Ba2+ | - |
Bos taurus |  |
| Ba2+ | - |
Homo sapiens | |
| Ba2+ | - |
Rattus norvegicus | |
| Ca2+ | - |
Bos taurus | |
| Ca2+ | - |
Homo sapiens | |
| Ca2+ | - |
Rattus norvegicus | |
| Li+ | 0.1 mM to 10 mM, the lithium inhibition profile is uncompetitive type | Bos taurus | |
| Li+ | 0.1 mM to 10 mM, the lithium inhibition profile is uncompetitive type | Homo sapiens | |
| Li+ | 0.1 mM to 10 mM, the lithium inhibition profile is uncompetitive type | Rattus norvegicus | |
| Mn2+ | - |
Bos taurus | |
| Mn2+ | - |
Homo sapiens | |
| Mn2+ | - |
Rattus norvegicus | |
Metals/Ions
| Metals/Ions | Comment | Organism | Structure |
|---|---|---|---|
| Mg2+ | 3 mM of Mg2+ is the optimal concentration | Homo sapiens | |
| Mg2+ | 3 mM of Mg2+ is the optimal concentration | Rattus norvegicus | |
| Mg2+ | 3 mM of Mg2+ is the optimal concentration | Bos taurus | |
Molecular Weight [Da]
| Molecular Weight [Da] | Molecular Weight Maximum [Da] | Comment | Organism |
|---|---|---|---|
| 29000 | - |
2 * 29000, SDS-PAGE | Bos taurus |
| 29000 | - |
x * 29000, SDS-PAGE | Rattus norvegicus |
| 58000 | - |
gel filtration | Bos taurus |
Natural Substrates/ Products (Substrates)
| Natural Substrates | Organism | Comment (Nat. Sub.) | Natural Products | Comment (Nat. Pro.) | Rev. | Reac. |
|---|---|---|---|---|---|---|
| alpha-D-galactose 1-phosphate + H2O | Homo sapiens | - |
D-galactose + phosphate | - |
? | |
| alpha-D-galactose 1-phosphate + H2O | Rattus norvegicus | - |
D-galactose + phosphate | - |
? | |
| alpha-D-galactose 1-phosphate + H2O | Bos taurus | - |
D-galactose + phosphate | - |
? | |
Organism
| Organism | UniProt | Comment | Textmining |
|---|---|---|---|
| Bos taurus | - |
- |
- |
| Homo sapiens | - |
- |
- |
| Rattus norvegicus | - |
- |
- |
Purification (Commentary)
| Purification (Comment) | Organism |
|---|---|
- |
Bos taurus |
Source Tissue
| Source Tissue | Comment | Organism | Textmining |
|---|---|---|---|
| brain | - |
Homo sapiens | - |
| brain | - |
Rattus norvegicus | - |
| brain | - |
Bos taurus | - |
Substrates and Products (Substrate)
| Substrates | Comment Substrates | Organism | Products | Comment (Products) | Rev. | Reac. |
|---|---|---|---|---|---|---|
| alpha-D-galactose 1-phosphate + H2O | - |
Homo sapiens | D-galactose + phosphate | - |
? | |
| alpha-D-galactose 1-phosphate + H2O | - |
Rattus norvegicus | D-galactose + phosphate | - |
? | |
| alpha-D-galactose 1-phosphate + H2O | - |
Bos taurus | D-galactose + phosphate | - |
? | |
| alpha-D-galactose 1-phosphate + H2O | the enzyme also has the activity of EC 3.1.3.25, inositol-phosphate phosphatase | Homo sapiens | D-galactose + phosphate | - |
? | |
| alpha-D-galactose 1-phosphate + H2O | the enzyme also has the activity of EC 3.1.3.25, inositol-phosphate phosphatase | Rattus norvegicus | D-galactose + phosphate | - |
? | |
| alpha-D-galactose 1-phosphate + H2O | the enzyme also has the activity of EC 3.1.3.25, inositol-phosphate phosphatase | Bos taurus | D-galactose + phosphate | - |
? | |
Subunits
| Subunits | Comment | Organism |
|---|---|---|
| ? | x * 29000, SDS-PAGE | Rattus norvegicus |
| dimer | 2 * 29000, SDS-PAGE | Bos taurus |
Temperature Stability [°C]
| Temperature Stability Minimum [°C] | Temperature Stability Maximum [°C] | Comment | Organism |
|---|---|---|---|
| 80 | - |
15 min, activity is unaffected | Homo sapiens |
| 80 | - |
15 min, activity is unaffected | Rattus norvegicus |
| 80 | - |
15 min, activity is unaffected | Bos taurus |
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Release 2023.1 (January 2023)
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