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Literature summary for 3.1.3.9 extracted from

  • Mahato, A.; Bhattacharya, S.; Shanthi, N.
    Design, synthesis and glucose-6-phosphatase inhibitory activity of diaminoguanidine analogues of 3-guanidinopropionic acid and amino substituted (pyridin-2-yl)thiourea derivatives (2011), J. Pharm. Sci. Res., 3, 896-902.
No PubMed abstract available
Search for more literature for 3.1.3.9

Inhibitors

Inhibitors Comment Organism Structure
1-propyl-3-(pyridin-2-yl)thiourea 40.71% inhibition Capra hircus
2-{[bis(hydrazine)methylene]amino}-4-methylpentanoic acid 2.61% inhibition Capra hircus
2-{[bis(hydrazino)methylene]amino}-3-(4-hydroxyphenyl)propanoic acid 6.61% inhibition Capra hircus
2-{[bis(hydrazino)methylene]amino}-3-hydroxybutanoic acid 11.68% inhibition Capra hircus
2-{[bis(hydrazino)methylene]amino}-3-hydroxypropanoic acid 10.56% inhibition Capra hircus
2-{[bis(hydrazino)methylene]amino}-3-methylpentanoic acid 3.37% inhibition Capra hircus
N-(pyridine-2-yl)morpholine-4-carbothioamide 35.32% inhibition Capra hircus
N-(pyridine-2-yl)piperidine-4-carbothioamide 38.88% inhibition Capra hircus

Organism

Organism UniProt Comment Textmining
Capra hircus
-
-
-

Source Tissue

Source Tissue Comment Organism Textmining
liver
-
 Capra hircus
-

Substrates and Products (Substrate)

Substrates Comment Substrates Organism Products Comment (Products) Rev. Reac.
D-glucose 6-phosphate + H2O
-
 Capra hircus D-glucose + phosphate
-
 ?

Synonyms

Synonyms Comment Organism
glucose-6-phosphatase
-
 Capra hircus

Temperature Optimum [°C]

Temperature Optimum [°C] Temperature Optimum Maximum [°C] Comment Organism
37
-
 assay at Capra hircus

pH Optimum

pH Optimum Minimum pH Optimum Maximum Comment Organism
6
-
 assay at Capra hircus