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Literature summary for 3.1.3.9 extracted from

  • Wang, D.; Wei, Y.; Schmoll, D.; Maclean, K.N.; Pagliassotti, M.J.
    Endoplasmic reticulum stress increases glucose-6-phosphatase and glucose cycling in liver cells (2006), Endocrinology, 147, 350-358.
    View publication on PubMed
Search for more literature for 3.1.3.9

Activating Compound

Activating Compound Comment Organism Structure
additional information endoplasmic stress, induced by treatment of hepatocytes with tunicamycin and thapsigargin, leads to induction of enzyme activity in hepatocytes, overview Rattus norvegicus

Cloned(Commentary)

Cloned (Comment) Organism
expression of the enzyme in H4IIE cells, determination of promoter activity and regulation, influences on enzyme expression by e.g. tunicamycin and thapsigargin, overview Rattus norvegicus

Localization

Localization Comment Organism GeneOntology No. Textmining
endoplasmic reticulum
-
 Rattus norvegicus 5783
-

Natural Substrates/ Products (Substrates)

Natural Substrates Organism Comment (Nat. Sub.) Natural Products Comment (Nat. Pro.) Rev. Reac.
additional information Rattus norvegicus endoplasmic stress may play a role in diabetes, and it results in increased enzyme activity in the liver, overview ?
-
 ?

Organism

Organism UniProt Comment Textmining
Rattus norvegicus
-
 male Wistar rats
-

Source Tissue

Source Tissue Comment Organism Textmining
H4IIE cell liver cell Rattus norvegicus
-
hepatocyte primary Rattus norvegicus
-
liver
-
 Rattus norvegicus
-

Substrates and Products (Substrate)

Substrates Comment Substrates Organism Products Comment (Products) Rev. Reac.
additional information endoplasmic stress may play a role in diabetes, and it results in increased enzyme activity in the liver, overview Rattus norvegicus ?
-
 ?

Synonyms

Synonyms Comment Organism
G6Pase
-
 Rattus norvegicus