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Literature summary for 3.1.3.88 extracted from

  • Kudo, F.; Fujii, T.; Kinoshita, S.; Eguchi, T.
    Unique O-ribosylation in the biosynthesis of butirosin (2007), Bioorg. Med. Chem., 15, 4360-4368.
    View publication on PubMed
Search for more literature for 3.1.3.88

Cloned(Commentary)

Cloned (Comment) Organism
expressed in Escherichia coli BL21(DE3) cells Niallia circulans

Inhibitors

Inhibitors Comment Organism Structure
additional information EDTA does not affect the enzyme activity Niallia circulans

Metals/Ions

Metals/Ions Comment Organism Structure
additional information the enzyme does not need a (divalent) metal ion for activity Niallia circulans

Organism

Organism UniProt Comment Textmining
Niallia circulans
-
-
-
Niallia circulans SANK72073
-
-
-

Purification (Commentary)

Purification (Comment) Organism
DEAE-Sephadex gel filtration and Superdex 200 gel filtration Niallia circulans

Substrates and Products (Substrate)

Substrates Comment Substrates Organism Products Comment (Products) Rev. Reac.
4-nitrophenyl phosphate + H2O
-
 Niallia circulans 4-nitrophenol + phosphate
-
 ?
4-nitrophenyl phosphate + H2O
-
 Niallia circulans SANK72073 4-nitrophenol + phosphate
-
 ?
5''-phosphoribostamycin + H2O
-
 Niallia circulans ribostamycin + phosphate
-
 ?
5''-phosphoribostamycin + H2O
-
 Niallia circulans SANK72073 ribostamycin + phosphate
-
 ?
D-fructose-1,6-bisphosphate + H2O rapid hydrolysis Niallia circulans ?
-
 ?
D-fructose-1,6-bisphosphate + H2O rapid hydrolysis Niallia circulans SANK72073 ?
-
 ?
additional information PRPP, fructose-6-phosphate, ribose-5-phosphate, and nucleotides (AMP, CMP, GMP, UMP, and dTMP) are not hydrolyzed Niallia circulans ?
-
 ?
additional information PRPP, fructose-6-phosphate, ribose-5-phosphate, and nucleotides (AMP, CMP, GMP, UMP, and dTMP) are not hydrolyzed Niallia circulans SANK72073 ?
-
 ?

Synonyms

Synonyms Comment Organism
btrP
-
 Niallia circulans

General Information

General Information Comment Organism
metabolism the enzyme is responsible for the formation of the key ribostamycin intermediate in the biosynthesis of butirosin Niallia circulans