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Literature summary for 3.1.3.86 extracted from

  • Drayer, A.; Pesesse, X.; De Smedt, F.; Communi, D.; Moreau, C.; Erneux, C.
    The family of inositol and phosphatidylinositol polyphosphate 5-phosphatases (1996), Biochem. Soc. Trans., 24, 1001-1005.
    View publication on PubMed
Search for more literature for 3.1.3.86

Cloned(Commentary)

Cloned (Comment) Organism
expressed in COS-7 cells Homo sapiens

Inhibitors

Inhibitors Comment Organism Structure
additional information the enzyme is insensitive to N-ethylmaleimide, InsPh and 2,3-bisphosphoglycerate Rattus norvegicus

Molecular Weight [Da]

Molecular Weight [Da] Molecular Weight Maximum [Da] Comment Organism
145000
-
 gel filtration Homo sapiens
145000
-
 gel filtration Rattus norvegicus

Organism

Organism UniProt Comment Textmining
Homo sapiens
-
-
-
Rattus norvegicus
-
-
-

Source Tissue

Source Tissue Comment Organism Textmining
brain
-
 Homo sapiens
-
brain
-
 Rattus norvegicus
-
placenta
-
 Homo sapiens
-

Substrates and Products (Substrate)

Substrates Comment Substrates Organism Products Comment (Products) Rev. Reac.
1-phosphatidyl-1D-myo-inositol 1,3,4,5-tetrakisphosphate + H2O
-
 Homo sapiens 1-phosphatidyl-1D-myo-inositol 1,3,4-trisphosphate + phosphate
-
 ?
1-phosphatidyl-1D-myo-inositol 1,3,4,5-tetrakisphosphate + H2O
-
 Rattus norvegicus 1-phosphatidyl-1D-myo-inositol 1,3,4-trisphosphate + phosphate
-
 ?
1-phosphatidyl-1D-myo-inositol 3,4,5-trisphosphate + H2O
-
 Homo sapiens 1-phosphatidyl-1D-myo-inositol 3,4-bisphosphate + phosphate
-
 ?
1-phosphatidyl-1D-myo-inositol 3,4,5-trisphosphate + H2O
-
 Rattus norvegicus 1-phosphatidyl-1D-myo-inositol 3,4-bisphosphate + phosphate
-
 ?

Synonyms

Synonyms Comment Organism
PtdIns(3,4,5)P3 5-phosphatase
-
 Homo sapiens
PtdIns(3,4,5)P3 5-phosphatase
-
 Rattus norvegicus
SH2 domain containing 5-phosphatase
-
 Homo sapiens
SHIP
-
 Homo sapiens