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Literature summary for 3.1.3.85 extracted from

  • Uddin, R.; Zahra, N.; Azam, S.
    Identification of glucosyl-3-phosphoglycerate phosphatase as a novel drug target against resistant strain of Mycobacterium tuberculosis (XDR1219) by using comparative metabolic pathway approach (2019), Comput. Biol. Chem., 79, 91-102 .
    View publication on PubMed
Search for more literature for 3.1.3.85

Localization

Localization Comment Organism GeneOntology No. Textmining
cytoplasm
-
 Mycobacterium tuberculosis 5737
-

Natural Substrates/ Products (Substrates)

Natural Substrates Organism Comment (Nat. Sub.) Natural Products Comment (Nat. Pro.) Rev. Reac.
2-O-(alpha-D-glucopyranosyl)-3-phospho-D-glycerate + H2O Mycobacterium tuberculosis
-
 2-O-(alpha-D-glucopyranosyl)-D-glycerate + phosphate
-
 ?
2-O-(alpha-D-glucopyranosyl)-3-phospho-D-glycerate + H2O Mycobacterium tuberculosis H37Rv
-
 2-O-(alpha-D-glucopyranosyl)-D-glycerate + phosphate
-
 ?

Organism

Organism UniProt Comment Textmining
Mycobacterium tuberculosis P9WIC7
-
-
Mycobacterium tuberculosis H37Rv P9WIC7
-
-

Substrates and Products (Substrate)

Substrates Comment Substrates Organism Products Comment (Products) Rev. Reac.
2-O-(alpha-D-glucopyranosyl)-3-phospho-D-glycerate + H2O
-
 Mycobacterium tuberculosis 2-O-(alpha-D-glucopyranosyl)-D-glycerate + phosphate
-
 ?
2-O-(alpha-D-glucopyranosyl)-3-phospho-D-glycerate + H2O
-
 Mycobacterium tuberculosis H37Rv 2-O-(alpha-D-glucopyranosyl)-D-glycerate + phosphate
-
 ?
additional information the enzyme has residual mutase activity but it prefers glucosyl-3-phosphoglycerate over 2-phosphoglycerate as a substrate Mycobacterium tuberculosis ?
-
 ?
additional information the enzyme has residual mutase activity but it prefers glucosyl-3-phosphoglycerate over 2-phosphoglycerate as a substrate Mycobacterium tuberculosis H37Rv ?
-
 ?

Synonyms

Synonyms Comment Organism
GpgP
-
 Mycobacterium tuberculosis

General Information

General Information Comment Organism
metabolism the protein is involved in the biosynthesis of methylglucose lipopolysaccharides which regulate the biosynthesis of mycolic acid Mycobacterium tuberculosis