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Literature summary for 3.1.3.68 extracted from

  • Toivari, M.H.; Ruohonen, L.; Miasnikov, A.N.; Richard, P.; Penttila, M.
    Metabolic engineering of Saccharomyces cerevisiae for conversion of D-glucose to xylitol and other five-carbon sugars and sugar alcohols (2007), Appl. Environ. Microbiol., 73, 5471-5476.
    View publication on PubMedView publication on EuropePMC

Cloned(Commentary)

Cloned (Comment) Organism
overexpression of DOG1 in Saccharomyces cerevisiae transketolase-deficient strain H1520 containing the integrated xylitol dehydrogenase-encoding gene (XYL2) gene increases the excretion of ribitol (by 1.6fold) and D-ribose (by 3.8fold) compared to the strain lacking DOG1 Saccharomyces cerevisiae

Metals/Ions

Metals/Ions Comment Organism Structure
Mg2+
-
Saccharomyces cerevisiae

Organism

Organism UniProt Comment Textmining
Saccharomyces cerevisiae
-
-
-

Specific Activity [micromol/min/mg]

Specific Activity Minimum [µmol/min/mg] Specific Activity Maximum [µmol/min/mg] Comment Organism
additional information
-
2-deoxy-glucose 6-phosphate (100%), D-ribulose 5-phosphate (7%), D-ribose 5-phosphate (42%), D-xylulose 5-phosphate (15%) Saccharomyces cerevisiae

Substrates and Products (Substrate)

Substrates Comment Substrates Organism Products Comment (Products) Rev. Reac.
2-Deoxy-D-glucose 6-phosphate + H2O
-
Saccharomyces cerevisiae 2-Deoxy-D-glucose + phosphate
-
?
D-ribose 5-phosphate + H2O
-
Saccharomyces cerevisiae D-ribose + phosphate
-
?
D-ribulose 5-phosphate + H2O
-
Saccharomyces cerevisiae D-ribulose + phosphate
-
?
D-xylulose 5-phosphate + H2O
-
Saccharomyces cerevisiae D-xylulose + phosphate
-
?

Synonyms

Synonyms Comment Organism
2-deoxy-glucose 6-phosphate phosphatase
-
Saccharomyces cerevisiae
DOG1
-
Saccharomyces cerevisiae

pH Optimum

pH Optimum Minimum pH Optimum Maximum Comment Organism
7
-
assay at Saccharomyces cerevisiae