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Literature summary for 3.1.3.67 extracted from

  • Haas-Kogan, D.; Shalev, N.; Wong, M.; Mills, G.; Yount, G.; Stokoe, D.
    Protein kinase B (PKB/Akt) activity is elevated in glioblastoma cells due to mutation of the tumor suppressor PTEN/MMAC (1998), Curr. Biol., 8, 1195-1198.
    View publication on PubMed

Natural Substrates/ Products (Substrates)

Natural Substrates Organism Comment (Nat. Sub.) Natural Products Comment (Nat. Pro.) Rev. Reac.
additional information Homo sapiens the enzyme plays a role in regulating the activity of the phosphatidylinositol 3-kinase pathway in malignant cells ?
-
?

Organism

Organism UniProt Comment Textmining
Homo sapiens
-
-
-

Source Tissue

Source Tissue Comment Organism Textmining
astrocyte primary astrocyte, expression of wild-type enzyme Homo sapiens
-
glioblastoma cell expression of mutant forms of PTEN Homo sapiens
-

Substrates and Products (Substrate)

Substrates Comment Substrates Organism Products Comment (Products) Rev. Reac.
additional information the enzyme plays a role in regulating the activity of the phosphatidylinositol 3-kinase pathway in malignant cells Homo sapiens ?
-
?

Synonyms

Synonyms Comment Organism
PTEN/MMAC
-
Homo sapiens