Literature summary for 3.1.3.66 extracted from

Sung, J.Y.; Na, K.; Kim, H.S.
Down-regulation of inositol polyphosphate 4-phosphatase type II expression in colorectal carcinoma (2017), Anticancer Res., 37, 5525-5531 .

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Application

Application	Comment	Organism
medicine	colorectal carcinoma cell lines HCT-116, SW-620, DLD-1, and WiDr express significantly lower levels of INPP4B protein than the normal colonic epithelial cell lines CCD-841 CoTr and FHC. INPP4B mRNA expression in the colorectal carcinoma cell lines is significantly lower than in the normal colonic epithelial cells. Normal colonic mucosa displays uniform and strong-to-moderate INPP4B immunoreactivity, whereas 60.7% and 76.5% of the primary and metastatic colorectal carcinoma tissue samples exhibit reduced INPP4B expression, respectively	Homo sapiens

Organism

Organism	UniProt	Comment	Textmining
Homo sapiens	O15327	-	-

Source Tissue

Source Tissue	Comment	Organism	Textmining
DLD-1 cell	-	Homo sapiens	-
HCT-116 cell	-	Homo sapiens	-
SW-620 cell	-	Homo sapiens	-
WiDr cell	-	Homo sapiens	-

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Release 2023.1 (January 2023)