Literature summary for 3.1.3.66 extracted from

Barnache, S.; Le Scolan, E.; Kosmider, O.; Denis, N.; Moreau-Gachelin, F.
Phosphatidylinositol 4-phosphatase type II is an erythropoietin-responsive gene (2006), Oncogene, 25, 1420-1423.

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Application

Application	Comment	Organism
medicine	physiological role of PI-4-phosphatase II in the proerythroblast by controlling erythropoetin-resonsiveness through a negative regualtion of the PI3K/Akt pathway is demonstrated	Mus musculus

Organism

Organism	UniProt	Comment	Textmining
Mus musculus	-	-	-

Source Tissue

Source Tissue	Comment	Organism	Textmining
additional information	phosphatidylinositol 4-phosphatase type II gene expression is turned off in malignant proerythroblasts of spi-1/PU.1 transgenic mice developing erythroleukemia. Stimulation of malignant cells with erythropoetin inudces PI-4-phosphatase II transcription pointing this gene as an erythropoetin-responsive gene	Mus musculus	-

Synonyms

Synonyms	Comment	Organism
phosphatidylinositol 4-phosphatase type II	-	Mus musculus
PI-4-phosphatase II	-	Mus musculus

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Release 2023.1 (January 2023)